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Academic Article Plasma concentrations of immunoreactive atrial natriuretic peptide in hospitalized cirrhotic and noncirrhotic patients: evidence for a role of deficient atrial natriuretic peptide in pathogenesis of cirrhotic ascites.
Concept Methyldopa
Concept Medicine, Chinese Traditional
Concept MAP Kinase Signaling System
Concept Antineoplastic Combined Chemotherapy Protocols
Concept Humans
Concept Autoimmune Diseases
Concept Cytochrome P-450 CYP1A2
Concept Ursodeoxycholic Acid
Concept Doxorubicin
Concept Antigens, Differentiation, T-Lymphocyte
Concept Down-Regulation
Concept Hot Temperature
Concept Cattle
Concept Acetamides
Concept Chromatography, Ion Exchange
Concept Spinal Cord
Concept Heme
Concept Rabbits
Concept Potassium Chloride
Concept Glucose Transporter Type 4
Concept Electrophoresis, Polyacrylamide Gel
Concept Candida
Concept Lymphocytes
Concept Fluorometry
Concept Cocarcinogenesis
Concept Longitudinal Studies
Concept Proto-Oncogene Proteins c-myc
Concept alpha-MSH
Concept Tetrazolium Salts
Concept Glucuronates
Concept Adverse Drug Reaction Reporting Systems
Concept Autoantibodies
Concept Vaccinia virus
Concept Mephenytoin
Concept Synapses
Concept Cause of Death
Concept Porins
Concept Hepatitis B Core Antigens
Concept Transcription Factor AP-1
Concept Acetylcholine
Concept Microsatellite Repeats
Concept Methylcholanthrene
Concept Antibodies, Monoclonal
Concept Arsenites
Concept Hypergammaglobulinemia
Concept Cytoplasmic Granules
Concept Cryoglobulins
Concept Analysis of Variance
Concept Weight Loss
Concept Benzoates
Concept Rheumatoid Factor
Concept Sexual Behavior
Concept Abdominal Pain
Concept Ellipticines
Concept Lymphocyte Activation
Concept Bone Diseases, Metabolic
Concept Response Elements
Concept Antioxidants
Concept Antimalarials
Concept Antigens, Viral
Concept Oxidation-Reduction
Concept Cost-Benefit Analysis
Concept Chromosomes, Human, Pair 19
Concept Protein Stability
Concept Cytochrome P-450 CYP1A1
Concept Arthralgia
Concept Cholangitis
Concept Cytochrome b Group
Concept Leukocytes, Mononuclear
Concept alpha-Fetoproteins
Concept Dithionite
Concept Glutamates
Concept Polychlorinated Biphenyls
Concept Carcinoma, Hepatocellular
Concept Binding Sites
Concept Herbal Medicine
Concept Rats, Inbred F344
Concept Interleukin-8
Concept beta-Thalassemia
Concept Administration, Oral
Concept History, 19th Century
Concept Lysosomes
Concept Hemolysis
Concept China
Concept Liver Function Tests
Concept Depression
Concept Menopause
Concept Genetic Testing
Concept Amino Acids
Concept Combined Modality Therapy
Concept Thrombocytopenia
Concept Aflatoxins
Concept Amino Acid Substitution
Concept Lymphocyte Function-Associated Antigen-1
Concept Antibodies, Antinuclear
Concept Receptors, Transferrin
Concept Erythrocytes
Concept Choline Deficiency
Concept Binding, Competitive
Concept Blotting, Northern
Concept Vitamin E
Concept Chemotactic Factors
Concept Thiazolidinediones
Concept Mammals
Concept Aged
Concept Dermatitis, Phototoxic
Concept Bile Duct Diseases
Concept Camellia sinensis
Concept Adenosine Triphosphate
Concept Amino Acid Sequence
Concept Lipase
Concept Protoporphyrins
Concept Patient Education as Topic
Concept Mice, Knockout
Concept Osteoarthritis
Concept NADH Dehydrogenase
Concept Cohort Studies
Concept Antibodies
Concept Sarcolemma
Concept Prothrombin
Concept Databases, Genetic
Concept Cytochrome P-450 Enzyme System
Concept Lipid Peroxidation
Concept Antiviral Agents
Concept Calcium
Concept Anti-Anxiety Agents
Concept Acute Disease
Concept Hydrogen Peroxide
Concept Polybrominated Biphenyls
Concept Antibodies, Viral
Concept Blotting, Western
Concept Histocompatibility Antigens Class I
Concept Ascorbic Acid
Concept Antigens, Differentiation, Myelomonocytic
Concept Osteocalcin
Concept Guillain-Barre Syndrome
Concept Enhancer Elements, Genetic
Concept Chloramphenicol O-Acetyltransferase
Concept Triazoles
Concept T-Lymphocyte Subsets
Concept Acetylcysteine
Concept Pathology, Molecular
Concept Hydroxymethylglutaryl-CoA Reductase Inhibitors
Concept Biopsy
Concept Dithiothreitol
Concept Cardiac Output
Concept Mesenteric Arteries
Concept Anal Canal
Concept Sphingosine
Concept Immunoglobulins
Concept Drinking Behavior
Concept Clinical Protocols
Concept Chromatography, Liquid
Concept Up-Regulation
Concept Biopsy, Needle
Concept Durapatite
Concept Fibrinolysis
Concept Stroke Volume
Concept Iron-Binding Proteins
Concept Immunoprecipitation
Concept Chromatography, Gel
Concept Carcinogens
Concept Phenylephrine
Concept Spectrometry, Mass, Electrospray Ionization
Concept Genetic Markers
Concept Mice
Concept Cell Line, Transformed
Concept Bone Marrow Cells
Concept Epilepsy
Concept Delayed Diagnosis
Concept Histocytochemistry
Concept 2-Acetylaminofluorene
Concept Serum
Concept Kinetics
Concept Adipokines
Concept Hep G2 Cells
Concept Biological Transport, Active
Concept Flavonoids
Concept Transcription, Genetic
Concept Brain Chemistry
Concept Pyrroles
Concept Plasmapheresis
Concept ets-Domain Protein Elk-1
Concept Antihypertensive Agents
Concept Tumor Necrosis Factor-alpha
Concept Methemoglobin
Concept Claudins
Concept Chromatography, High Pressure Liquid
Concept Liver Diseases, Alcoholic
Concept Splanchnic Circulation
Concept Serum Albumin
Concept Antipyrine
Concept Hydroxyapatites
Concept Tryptophan
Concept Fatty Liver, Alcoholic
Concept Exons
Concept Diabetes Mellitus, Type 2
Concept Mice, Inbred C57BL
Concept Regulatory Sequences, Nucleic Acid
Concept HLA-DR Antigens
Concept Hepatitis B e Antigens
Concept Retrospective Studies
Concept Enzyme Activation
Concept Platelet Count
Concept Transferrin
Concept Computational Biology
Concept Mitochondria, Liver
Concept Consensus Sequence
Concept RNA Stability
Concept Hepatitis B, Chronic
Concept Alanine Transaminase
Concept Blood Platelets
Concept T-Lymphocytes
Concept Silymarin
Concept Mitochondria, Heart
Concept Tetrapyrroles
Concept Alcoholism
Concept Multivariate Analysis
Concept Oxygen
Concept Cadmium
Concept Cobalt
Concept Antigens, CD
Concept Chickens
Concept Phlebotomy
Concept MAP Kinase Kinase 1
Concept Serotonin Plasma Membrane Transport Proteins
Concept Signal Transduction
Concept Biliverdine
Concept Spectrophotometry
Concept North America
Concept Biomedical Research
Concept Intestine, Small
Concept Immunoglobulin G
Concept Body Mass Index
Concept Tandem Mass Spectrometry
Concept Nuclear Receptor Subfamily 1, Group D, Member 1
Concept Diagnosis, Differential
Concept Vascular Endothelial Growth Factor A
Concept Enzyme-Linked Immunosorbent Assay
Concept Protein Binding
Concept Neutrophils
Concept T-Lymphocytes, Cytotoxic
Concept Intestinal Mucosa
Concept Haptoglobins
Concept Uroporphyrinogen Decarboxylase
Concept Liver Circulation
Concept Apoptosis
Concept Interleukin-10
Concept Somatotypes
Concept Calcium Channel Blockers
Concept Protein Transport
Concept Narcotics
Concept Necrosis
Concept Hepatitis, Alcoholic
Concept Anti-Bacterial Agents
Concept Databases, Factual
Concept Mixed Function Oxygenases
Concept Thiazoles
Concept Terminology as Topic
Concept Methionine Sulfoximine
Concept Chromans
Concept RNA, Small Interfering
Concept Androgens
Concept Rectal Neoplasms
Concept Mass Spectrometry
Concept Esophageal and Gastric Varices
Concept Protein Processing, Post-Translational
Concept Genetic Association Studies
Concept Cytotoxicity Tests, Immunologic
Concept Vasoconstriction
Concept Receptors, Antigen, T-Cell
Concept Microchemistry
Concept Serum Albumin, Bovine
Concept Drug Eruptions
Concept Colonoscopy
Concept Restriction Mapping
Concept Allantois
Concept Mitochondria
Concept Brain
Concept Flow Cytometry
Concept Aged, 80 and over
Concept Circadian Rhythm
Concept Liver Cirrhosis, Biliary
Concept Complementarity Determining Regions
Concept Introns
Concept Glutamic Acid
Concept Erythropoietin
Concept Spectrophotometry, Atomic
Concept Insulin Receptor Substrate Proteins
Concept Metalloporphyrins
Concept Calcium-Calmodulin-Dependent Protein Kinases
Concept Rats, Inbred Strains
Concept Cell Nucleus
Concept Cytochromes b5
Concept Anemia, Hemolytic, Autoimmune
Concept Calibration
Concept Liver Regeneration
Concept Safety
Concept Actins
Concept Fatty Acid-Binding Proteins
Concept Myosins
Concept Intercellular Adhesion Molecule-1
Concept Membrane Potentials
Concept Drug Costs
Concept Bone and Bones
Concept Cholangiopancreatography, Endoscopic Retrograde
Concept Piperonyl Butoxide
Concept Mitochondrial Membranes
Concept Isoproterenol
Concept Telomere
Concept Body Weight
Concept CD8-Positive T-Lymphocytes
Concept Lymphocyte Count
Concept Ubiquitination
Concept Atenolol
Concept Alcohol Drinking
Concept Vascular Cell Adhesion Molecule-1
Concept Cholecystectomy
Concept NG-Nitroarginine Methyl Ester
Concept Aflatoxin B1
Concept Hemin
Concept Aminolevulinic Acid
Concept Ceruloplasmin
Concept DNA Fragmentation
Concept Calcium Channels, T-Type
Concept Porphobilinogen
Concept National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Concept Chemokine CCL3
Concept Genomics
Concept TATA Box
Concept Rectum
Concept Porphyrins
Concept Methoxamine
Concept Case-Control Studies
Concept Chemokines, CXC
Concept Hemodynamics
Concept NF-E2-Related Factor 2
Concept Chemokine CCL2
Concept Spectrometry, Fluorescence
Concept Carboxy-Lyases
Concept Antibody Specificity
Concept Anti-Infective Agents, Urinary
Concept Prospective Studies
Concept Electron Transport
Concept Leptin
Concept Basic-Leucine Zipper Transcription Factors
Concept 3' Untranslated Regions
Concept Porphyria, Acute Intermittent
Concept Cross-Sectional Studies
Concept Rats
Concept Sterol Esterase
Concept Allylisopropylacetamide
Concept Hepatitis, Autoimmune
Concept African Americans
Concept alpha 1-Antitrypsin Deficiency
Concept Cholestasis
Concept Hemoglobins
Concept Genistein
Concept Ferritins
Concept Stress, Psychological
Concept Sequence Homology, Nucleic Acid
Concept Coproporphyrins
Concept Substrate Specificity
Concept Genome-Wide Association Study
Concept Vasodilation
Concept Benzamides
Concept Catechin
Concept Multiple Sclerosis
Concept Immunoelectrophoresis
Concept HLA Antigens
Concept Proteomics
Concept Creatinine
Concept Amoxicillin-Potassium Clavulanate Combination
Concept Tetanus Toxin
Concept Rats, Wistar
Concept Analgesics
Concept Leucine Zippers
Concept STAT1 Transcription Factor
Concept Oligonucleotide Array Sequence Analysis
Concept B-Lymphocytes
Concept Middle Aged
Concept STAT2 Transcription Factor
Concept Rats, Sprague-Dawley
Concept beta-Galactosidase
Concept Chromatography
Concept Buthionine Sulfoximine
Concept United States
Concept Host-Pathogen Interactions
Concept Protein Conformation
Concept Acetaminophen
Concept Sunlight
Concept Colon
Concept Phytotherapy
Concept Hepatitis C, Chronic
Concept MicroRNAs
Concept Bilirubin
Concept Portasystemic Shunt, Surgical
Concept Young Adult
Concept Promoter Regions, Genetic
Concept Copper
Concept Cation Transport Proteins
Concept Base Sequence
Concept Amino Acid Motifs
Concept Follow-Up Studies
Concept Zebrafish
Concept Killer Cells, Natural
Concept Immunohistochemistry
Concept Choline
Concept Antidepressive Agents
Concept Cell Line, Tumor
Concept Antibiotics, Antineoplastic
Concept Kynurenine
Concept Rats, Transgenic
Concept Cryoglobulinemia
Concept NADPH-Ferrihemoprotein Reductase
Concept Chemokine CXCL12
Concept Bile Ducts
Concept Hemopexin
Concept Phosphorylation
Concept Uroporphyrins
Academic Article Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh).
Academic Article Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of hepatic hemoproteins and regulatory heme pools.
Academic Article Iron and the liver.
Academic Article Activation of the hepatocarcinogen aflatoxin B1 by forms of human hepatic cytochromes P-450: some do and some don't.
Academic Article A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. I. Short-term effects on liver function.
Academic Article A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition.
Academic Article Osteocalcin and bone alkaline phosphatase in the serum of women with liver disease.
Academic Article Immunochemical studies of haem oxygenase. Preparation and characterization of antibodies to chick liver haem oxygenase and their use in detecting and quantifying amounts of haem oxygenase protein.
Academic Article Synergistic induction of delta-aminolevulinate synthase by glutethimide and iron: relationship to the synergistic induction of heme oxygenase.
Academic Article Cloning, sequencing and expression of cDNA for chick liver haem oxygenase. Comparison of avian and mammalian cDNAs and deduced proteins.
Academic Article Purification and characterization of heme oxygenase from chick liver. Comparison of the avian and mammalian enzymes.
Academic Article Antibodies against mitochondrial dehydrogenase complexes in primary biliary cirrhosis.
Academic Article Mechanism of synergistic induction of hepatic heme oxygenase by glutethimide and iron: studies in cultured chick embryo liver cells.
Academic Article Four-hour measurement of urinary iron excretion after deferoxine treatment: a rapid, simple method for study of iron excretion.
Academic Article Prevalence and prediction of osteopenia in chronic liver disease.
Academic Article Usefulness and limitations of laboratory and hepatic imaging studies in iron-storage disease.
Academic Article Choline may be an essential nutrient in malnourished patients with cirrhosis.
Academic Article The porphyrias.
Academic Article Atenolol for prevention of rebleeding from esophageal varices in hepatic cirrhosis: results of a controlled, randomized pilot study.
Academic Article Heme catabolism in cultured hepatocytes: evidence that heme oxygenase is the predominant pathway and that a proportion of synthesized heme is converted rapidly to biliverdin.
Academic Article Mechanism of iron potentiation of hepatic uroporphyria: studies in cultured chick embryo liver cells.
Academic Article Immunoreactive uroporphyrinogen decarboxylase in the liver in porphyria cutanea tarda.
Academic Article Immunochemical detection of different isoenzymes of cytochrome P-450 induced in chick hepatocyte cultures.
Academic Article Hepatic microsomal function in rats with chronic dietary iron overload.
Academic Article Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide.
Academic Article Hepatic heme and drug metabolism in rats with chronic mountain sickness.
Academic Article Role of cytochrome P-450 in porphyria caused by halogenated aromatic compounds.
Academic Article Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals.
Academic Article Tryptophan 2,3-dioxygenase in chick embryo hepatocytes: studies in ovo and in culture.
Academic Article Microassay of heme oxygenase by high-performance liquid chromatography: application to assay of needle biopsies of human liver.
Academic Article Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450.
Academic Article Effects of therapeutic paracentesis on systemic and hepatic hemodynamics and on renal and hormonal function.
Academic Article Induction of porphyria in cultured chick-embryo hepatocytes by halogenated aromatic compounds.
Academic Article Hepatic heme synthesis in a new model of experimental hemochromatosis: studies in rats fed finely divided elemental iron.
Academic Article High-performance liquid chromatographic separation and quantitation of tetrapyrroles from biological materials.
Academic Article Induction of 5-aminolaevulinate synthase by two- to five-carbon alcohols in cultured chick-embryo hepatocytes. Relationship to induction of cytochrome P-450.
Academic Article Fatal liver failure in protoporphyria. Synergism between ethanol excess and the genetic defect.
Academic Article Severe liver injury due to phenelzine with unique hepatic deposition of extracellular material.
Academic Article Cytochrome P450 of small intestinal epithelial cells. Immunochemical characterization of the increase in cytochrome P450 caused by phenobarbital.
Academic Article Conversion of 5-aminolaevulinate into haem by homogenates of human liver. Comparison with rat and chick-embryo liver homogenates.
Academic Article Increased glutathione in cultured hepatocytes associated with induction of cytochrome P-450. Lack of effect of glutathione depletion on induction of cytochrome P-450 and delta-aminolevulinate synthase.
Academic Article Inhibition of uroporphyrinogen decarboxylase by halogenated biphenyls in chick hepatocyte cultures. Essential role for induction of cytochrome P-448.
Academic Article Formation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamide.
Academic Article Effect of uroporphyrin on the spectral measurement of cytochrome P450.
Academic Article Effect of hemochromatosis on hepatic cytochrome P450 and antipyrine metabolism in humans.
Academic Article High prevalence of serological markers of autoimmunity in patients with chronic hepatitis C.
Academic Article Distribution of iron in the liver predicts the response of chronic hepatitis C infection to interferon therapy.
Academic Article A detailed analysis of the Knodell score and other histologic parameters as predictors of response to interferon therapy in chronic hepatitis C.
Academic Article Chronic leukocytoclastic vasculitis complicating HBV infection. Possible role of mutant forms of HBV in pathogenesis and persistence of disease.
Academic Article Putting the freeze on hepatitis C virus-associated mixed cryoglobulinemia.
Academic Article Tissue distribution of zinc-mesoporphyrin in rats: relationship to inhibition of heme oxygenase.
Academic Article Effects of mifepristone (RU-486) on heme metabolism and cytochromes P-450 in cultured chick embryo liver cells, possible implications for acute porphyria.
Academic Article Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria.
Academic Article Colonic mucosal appearance of Tangier disease in a new patient.
Academic Article The post-translational processing of myeloperoxidase is regulated by the availability of heme.
Academic Article Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells.
Academic Article Effects of hemopexin on heme-mediated repression of 5-aminolevulinate synthase and induction of heme oxygenase in cultured hepatocytes.
Academic Article Inflammatory cloacogenic polyp: three cases and literature review.
Academic Article Acute hepatic and renal toxicity from low doses of acetaminophen in the absence of alcohol abuse or malnutrition: evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency.
Academic Article Induction of heme oxygenase in intestinal epithelial cells: studies in Caco-2 cell cultures.
Academic Article 3,5,5-Trimethylhexanoylferrocene induction of heme oxygenase activity in normal hepatocytes.
Academic Article Nutritional supplementation in chronic liver disease: an analytical review.
Academic Article Mixed cryoglobulinemia in chronic hepatitis C infection. A clinicopathologic analysis of 10 cases and review of recent literature.
Academic Article Repression of hepatic delta-aminolevulinate synthase by heme and metalloporphyrins: relationship to inhibition of heme oxygenase.
Academic Article Advances in understanding and treating 'the little imitator,' acute porphyria.
Academic Article Purifying nascent mRNA from nuclear run-on assays using guanidinium isothiocyanate.
Academic Article Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme.
Academic Article Iron and chronic viral hepatitis: emerging evidence for an important interaction.
Academic Article High-dose interferon-alpha 2b for re-treatment of nonresponders or relapsing patients with chronic hepatitis C. A controlled randomized trial.
Academic Article Induction of heme oxygenase-1 in LMH cells. Comparison of LMH cells to primary cultures of chick embryo liver cells.
Academic Article Iron in liver diseases other than hemochromatosis.
Academic Article Effect of interferon therapy on bile duct inflammation in hepatitis C.
Academic Article An update on iron metabolism: summary of the Fifth International Conference on Disorders of Iron Metabolism.
Academic Article Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins.
Academic Article Regulation of metallothionein gene expression. Studies in transfected primary cultures of chick embryo liver cells.
Academic Article Haemopexin and uptake of haem by liver cells.
Academic Article Multiple chemical sensitivity syndrome and porphyria. A note of caution and concern.
Academic Article Iron and chronic viral hepatitis.
Academic Article Mechanism of induction of heme oxygenase by metalloporphyrins in primary chick embryo liver cells: evidence against a stress-mediated response.
Academic Article Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: potential implications for patients with acute porphyria.
Academic Article Regulation of expression of the human heme oxygenase-1 gene in transfected chick embryo liver cell cultures.
Academic Article Therapy of hepatitis C: other options.
Academic Article Utility of hepatic iron index in American patients with hereditary hemochromatosis: a multicenter study.
Academic Article Inflammatory markers in chronic hepatitis C.
Academic Article Frequency and distribution of DNA fragmentation as a marker of cell death in chronic liver diseases.
Academic Article Molecular cloning, characterization, and expression of the chicken heme oxygenase-1 gene in transfected primary cultures of chick embryo liver cells.
Academic Article Diagnosis of porphyric syndromes: a practical approach in the era of molecular biology.
Academic Article Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases.
Academic Article Management of acute attacks in the porphyrias.
Academic Article Porphyria cutanea tarda, hepatitis C, and HFE gene mutations in North America.
Academic Article Interleukin-8 and hIRH (SDF1-alpha/PBSF) mRNA expression and histological activity index in patients with chronic hepatitis C.
Academic Article Enhanced phenotypic expression of alpha-1-antitrypsin deficiency in an MZ heterozygote with chronic hepatitis C.
Academic Article Porphyrin loading of lipofuscin granules in inflamed striated muscle.
Academic Article Inefficient recognition of autologous viral sequences by intrahepatic hepatitis C virus-specific cytotoxic T lymphocytes in chronically infected subjects.
Academic Article Reduction of health-related quality of life in chronic hepatitis C and improvement with interferon therapy. The Consensus Interferon Study Group.
Academic Article The value of intravenous heme-albumin and plasmapheresis in reducing postoperative complications of orthotopic liver transplantation for erythropoietic protoporphyria.
Academic Article Increased heme oxygenase-1 gene expression in liver cells and splanchnic organs from portal hypertensive rats.
Academic Article Hepatic iron concentration: noninvasive estimation by means of MR imaging techniques.
Academic Article Effects of selected antihypertensives and analgesics on hepatic porphyrin accumulation: implications for clinical porphyria.
Academic Article Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis.
Academic Article IFN-alpha receptor mRNA expression in a United States sample with predominantly genotype 1a/I chronic hepatitis C liver biopsies correlates with response to IFN therapy.
Academic Article Heme oxygenase: recent advances in understanding its regulation and role.
Academic Article Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC).
Academic Article Effects of antidepressants and benzodiazepine-type anxiolytic agents on hepatic porphyrin accumulation in primary cultures of chick embryo liver cells.
Academic Article Effects of phenylarsine oxide on expression of heme oxygenase-1 reporter constructs in transiently transfected cultures of chick embryo liver cells.
Academic Article Hepatotoxicity due to troglitazone: report of two cases and review of adverse events reported to the United States Food and Drug Administration.
Academic Article Iron reduction before and during interferon therapy of chronic hepatitis C: results of a multicenter, randomized, controlled trial.
Academic Article Iron reduction as an adjuvant to interferon therapy in patients with chronic hepatitis C who have previously not responded to interferon: a multicenter, prospective, randomized, controlled trial.
Academic Article Induction of the heme oxygenase-1 gene by metalloporphyrins.
Academic Article Outcomes research in chronic viral hepatitis C: effects of interferon therapy.
Academic Article Upstream regulatory elements in chick heme oxygenase-1 promoter: a study in primary cultures of chick embryo liver cells.
Academic Article Role of HFE gene mutations in liver diseases other than hereditary hemochromatosis.
Academic Article Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria.
Academic Article Management of recurrent hepatitis C after liver transplantation: a concise review.
Academic Article Hepatitis C: a review and update.
Academic Article Hepatic iron concentration and total body iron stores in thalassemia major.
Academic Article Iron-induced liver injury.
Academic Article Ubiquitin as a marker of cell injury in nonalcoholic steatohepatitis.
Academic Article Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: role in modulating mesenteric vascular reactivity.
Academic Article Urea and hypertonicity increase expression of heme oxygenase-1 in murine renal medullary cells.
Academic Article Comparative effects of different doses of ribavirin plus interferon-alpha2b for therapy of chronic hepatitis C: results of a controlled, randomized trial.
Academic Article Extrahepatic manifestations of infection with hepatitis C virus.
Academic Article Induction of heme oxygenase-1 by phenylarsine oxide. Studies in cultured primary liver cells.
Academic Article Iron as a comorbid factor in chronic viral hepatitis.
Academic Article Benefits of chronic plasmapheresis and intravenous heme-albumin in erythropoietic protoporphyria after orthotopic liver transplantation.
Academic Article Mapping of the chick heme oxygenase-1 proximal promoter for responsiveness to metalloporphyrins.
Academic Article Intestinal expression of genes involved in iron absorption in humans.
Academic Article Hemochromatosis and porphyria.
Academic Article Severe cholestatic hepatitis caused by thiazolidinediones: risks associated with substituting rosiglitazone for troglitazone.
Academic Article Management of nonalcoholic steatohepatitis: an analytic review.
Academic Article Iron and HFE or TfR1 mutations as comorbid factors for development and progression of chronic hepatitis C.
Academic Article Optimal management of nonalcoholic fatty liver/steatohepatitis.
Academic Article Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane.
Academic Article Iron as a co-morbid factor in nonhemochromatotic liver disease.
Academic Article Peginterferon alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior treatment.
Academic Article Identification of key elements that are responsible for heme-mediated induction of the avian heme oxygenase-1 gene.
Academic Article Hepatic porphyrias: diagnosis and management.
Academic Article Evolution of the HALT-C Trial: pegylated interferon as maintenance therapy for chronic hepatitis C in previous interferon nonresponders.
Academic Article Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS.
Academic Article Hemochromatosis mutations in Iranians with hepatitis B virus infection.
Academic Article Fatal air and bile embolism after percutaneous liver biopsy and ERCP.
Academic Article Associations among clinical, immunological, and viral quasispecies measurements in advanced chronic hepatitis C.
Academic Article Association of hepatitis C virus infection with serum iron status: analysis of data from the third National Health and Nutrition Examination Survey.
Academic Article Recommendations for the diagnosis and treatment of the acute porphyrias.
Academic Article Evolution of the intrahepatic T cell repertoire during chronic hepatitis C virus infection.
Academic Article Comparison of amplification enzymes for Hepatitis C Virus quasispecies analysis.
Academic Article Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests: results of the HALT-C cohort.
Academic Article Haem repression of the housekeeping 5-aminolaevulinic acid synthase gene in the hepatoma cell line LMH.
Academic Article Serum alpha-fetoprotein levels in patients with advanced hepatitis C: results from the HALT-C Trial.
Academic Article No role of the -2518 promoter polymorphism of monocyte chemotactic protein-1 in chronic hepatitis C.
Academic Article Neurovisceral porphyrias: what a hematologist needs to know.
Academic Article Iron in nonhemochromatotic liver disorders.
Academic Article Liver transplantation for erythropoietic protoporphyria liver disease.
Academic Article Hepatotoxicity associated with supplements containing Chinese green tea (Camellia sinensis).
Academic Article Hepatitis C virus-specific immune responses and quasi-species variability at baseline are associated with nonresponse to antiviral therapy during advanced hepatitis C.
Academic Article HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells.
Academic Article Reconstitution of hematin for intravenous infusion.
Academic Article Hepatotoxicity due to extracts of Chinese green tea (Camellia sinensis): a growing concern.
Academic Article HCV RNA detection by TMA during the hepatitis C antiviral long-term treatment against cirrhosis (Halt-C) trial.
Academic Article Autoimmune hepatitis triggered by statins.
Academic Article Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin.
Academic Article Roles of iron and HFE mutations on severity and response to therapy during retreatment of advanced chronic hepatitis C.
Academic Article Impact of disease severity on outcome of antiviral therapy for chronic hepatitis C: Lessons from the HALT-C trial.
Academic Article Health-related quality of life in patients with chronic hepatitis C and advanced fibrosis.
Academic Article Impact of reducing peginterferon alfa-2a and ribavirin dose during retreatment in patients with chronic hepatitis C.
Academic Article Genetic aspects of porphyria cutanea tarda.
Academic Article Hepatic steatosis in hepatitis C: comparison of diabetic and nondiabetic patients in the hepatitis C antiviral long-term treatment against cirrhosis trial.
Academic Article Marked hyperbilirubinemia associated with the heme oxygenase-1 gene promoter microsatellite polymorphism in a boy with autoimmune hemolytic anemia.
Academic Article Serum measures of iron status and HFE gene mutations in patients with hepatitis B virus infection.
Academic Article Antiviral response of HCV genotype 1 to consensus interferon and ribavirin versus pegylated interferon and ribavirin.
Academic Article Phlebotomy improves therapeutic response to interferon in patients with chronic hepatitis C: a meta-analysis of six prospective randomized controlled trials.
Academic Article Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes.
Academic Article Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial.
Academic Article Relationship of serum fibrosis markers with liver fibrosis stage and collagen content in patients with advanced chronic hepatitis C.
Academic Article Blunted cytopenias and weight loss: new correlates of virologic null response to re-treatment of chronic hepatitis C.
Academic Article Vascular endothelium as a contributor of plasma sphingosine 1-phosphate.
Academic Article Zinc mesoporphyrin induces rapid and marked degradation of the transcription factor Bach1 and up-regulates HO-1.
Academic Article Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol.
Academic Article Case records of the Massachusetts General Hospital. Case 20-2008. A 57-year-old woman with abdominal pain and weakness after gastric bypass surgery.
Academic Article DNA polymorphisms and response to treatment in patients with chronic hepatitis C: results from the HALT-C trial.
Academic Article Efficacy and safety of peginterferon alfa-2a/ribavirin in methadone maintenance patients: randomized comparison of direct observed therapy and self-administration.
Academic Article Effects of silymarin on hepatitis C virus and haem oxygenase-1 gene expression in human hepatoma cells.
Academic Article Hereditary hemochromatosis: time for targeted screening.
Academic Article Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin.
Academic Article Incidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver disease.
Academic Article Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States.
Academic Article Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon.
Academic Article Serum fibrosis marker levels decrease after successful antiviral treatment in chronic hepatitis C patients with advanced fibrosis.
Academic Article Drug-Induced Liver Injury Network (DILIN) prospective study: rationale, design and conduct.
Academic Article Evolution of hepatic steatosis in patients with advanced hepatitis C: results from the hepatitis C antiviral long-term treatment against cirrhosis (HALT-C) trial.
Academic Article The neuromediator glutamate, through specific substrate interactions, enhances mitochondrial ATP production and reactive oxygen species generation in nonsynaptic brain mitochondria.
Academic Article Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.
Academic Article Weight-related effects on disease progression in the hepatitis C antiviral long-term treatment against cirrhosis trial.
Academic Article Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C.
Academic Article Effect of HCV RNA suppression during peginterferon alfa-2a maintenance therapy on clinical outcomes in the HALT-C trial.
Academic Article CTL escape mutations of core protein are more frequent in strains of HBeAg negative patients with low levels of HBV DNA.
Academic Article Predicting clinical and histologic outcomes based on standard laboratory tests in advanced chronic hepatitis C.
Academic Article Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells.
Academic Article Fibrosis progression in chronic hepatitis C: morphometric image analysis in the HALT-C trial.
Academic Article Drug-induced liver injury associated with statins.
Academic Article Merimepodib, pegylated interferon, and ribavirin in genotype 1 chronic hepatitis C pegylated interferon and ribavirin nonresponders.
Academic Article Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma.
Academic Article Zinc mesoporphyrin induces rapid proteasomal degradation of hepatitis C nonstructural 5A protein in human hepatoma cells.
Academic Article Changes in quality of life and sexual health are associated with low-dose peginterferon therapy and disease progression in patients with chronic hepatitis C.
Academic Article MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins.
Academic Article A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment.
Academic Article Complication rate of percutaneous liver biopsies among persons with advanced chronic liver disease in the HALT-C trial.
Academic Article Serum fibrosis markers are associated with liver disease progression in non-responder patients with chronic hepatitis C.
Academic Article A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis.
Academic Article Duloxetine hepatotoxicity: a case-series from the drug-induced liver injury network.
Academic Article Parallel microRNA and mRNA expression profiling of (genotype 1b) human hepatoma cells expressing hepatitis C virus.
Academic Article Effect of bovine serum albumin on mitochondrial respiration in the brain and liver of mice and rats.
Academic Article Maintenance peginterferon therapy and other factors associated with hepatocellular carcinoma in patients with advanced hepatitis C.
Academic Article Development and progression of portal hypertensive gastropathy in patients with chronic hepatitis C.
Academic Article Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology.
Academic Article Iron levels in hepatocytes and portal tract cells predict progression and outcomes of patients with advanced chronic hepatitis C.
Academic Article Structural analysis of heme proteins: implications for design and prediction.
Academic Article Excess mortality in patients with advanced chronic hepatitis C treated with long-term peginterferon.
Academic Article Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV.
Academic Article microRNAs: fad or future of liver disease.
Academic Article Mallory-Denk bodies are associated with outcomes and histologic features in patients with chronic hepatitis C.
Academic Article Extended interferon-alpha therapy accelerates telomere length loss in human peripheral blood T lymphocytes.
Academic Article Subcellular tissue proteomics of hepatocellular carcinoma for molecular signature discovery.
Academic Article Association of filamin A and vimentin with hepatitis C virus proteins in infected human hepatocytes.
Academic Article YKL-40 genetic polymorphisms and the risk of liver disease progression in patients with advanced fibrosis due to chronic hepatitis C.
Academic Article Neonatal androgenization exacerbates alcohol-induced liver injury in adult rats, an effect abrogated by estrogen.
Academic Article Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis.
Academic Article Serum proteomic profiling in patients with drug-induced liver injury.
Academic Article Chinese medicine for treatment of chronic hepatitis B.
Academic Article Antigen-specific T lymphocyte proliferation decreases over time in advanced chronic hepatitis C.
Academic Article The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes.
Academic Article Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series.
Academic Article DNA methylation patterns in alcoholics and family controls.
Academic Article Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs.
Academic Article Risk factors for porphyria cutanea tarda -the iron/HFE connection.
Academic Article A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus.
Academic Article Liver injury from tumor necrosis factor-a antagonists: analysis of thirty-four cases.
Academic Article Loss-of-function ferrochelatase and gain-of-function erythroid-specific 5-aminolevulinate synthase mutations causing erythropoietic protoporphyria and x-linked protoporphyria in North American patients reveal novel mutations and a high prevalence of X-linked protoporphyria.
Academic Article Presentation and outcomes with clinically apparent interferon beta hepatotoxicity.
Academic Article Heme status affects human hepatic messenger RNA and microRNA expression.
Academic Article Intravenous interferon administered during liver transplantation is not effective in preventing hepatitis C reinfection.
Academic Article Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations.
Academic Article Proteomic strategy for probing complementary lethality of kinase inhibitors against pancreatic cancer.
Academic Article Non-coding RNAs in hepatitis C-induced hepatocellular carcinoma: dysregulation and implications for early detection, diagnosis and therapy.
Academic Article Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance.
Academic Article Hepatotoxicity of anti-TNF agents.
Academic Article Drug-induced liver injury with autoimmune features.
Academic Article ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury.
Academic Article Acute porphyrias in the USA: features of 108 subjects from porphyrias consortium.
Academic Article Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network.
Academic Article Hepatitis B and liver transplantation: molecular and clinical features that influence recurrence and outcome.
Academic Article Clinically important features of porphyrin and heme metabolism and the porphyrias.
Academic Article Herbal dietary supplement associated hepatotoxicity: an upcoming workshop and need for research.
Academic Article MiR-122 decreases HCV entry into hepatocytes through binding to the 3' UTR of OCLN mRNA.
Academic Article Herbal products and the liver: a review of adverse effects and mechanisms.
Academic Article On stress and the liver: a chicken and egg conundrum.
Academic Article Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study.
Academic Article Differences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044.
Academic Article Evidence for the targeting by 2-oxo-dehydrogenase enzymes in the T cell response of primary biliary cirrhosis.
Academic Article Comparative analysis of portal hepatic infiltrating leucocytes in acute drug-induced liver injury, idiopathic autoimmune and viral hepatitis.
Academic Article Acute Porphyrias.
Academic Article Leukocyte expression of heme oxygenase-1 [hmox1] varies inversely with severity of tricuspid regurgitation in acute pulmonary embolism.
Academic Article Homeostasis of iron and hepcidin in erythropoietic protoporphyria.
Academic Article Comparison of functional variants in IFNL4 and IFNL3 for association with HCV clearance.
Academic Article Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy.
Academic Article Pitfalls in Erythrocyte Protoporphyrin Measurement for Diagnosis and Monitoring of Protoporphyrias.
Academic Article Recent insights into the biological functions of liver fatty acid binding protein 1.
Academic Article Hepatotoxicity Associated with the Use of Anti-TNF-a Agents.
Academic Article Clinical presentations and outcomes of bile duct loss caused by drugs and herbal and dietary supplements.
Academic Article Advances in the management of erythropoietic protoporphyria - role of afamelanotide.
Academic Article Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury.
Academic Article Development of a modified lymphocyte transformation test for diagnosing drug-induced liver injury associated with an adaptive immune response.
Grant HEPATIC HEME, CYTOCHROME P-450 AND DRUG METABOLISM
Grant Effect of Heme on mRNA and miRNA Profile
Academic Article Clinical, Biochemical, and Genetic Characterization of North American Patients With Erythropoietic Protoporphyria and X-linked Protoporphyria.
Academic Article Acute hepatic porphyrias: Recommendations for evaluation and long-term management.
Academic Article BMP4 promotes oxaliplatin resistance by an induction of epithelial-mesenchymal transition via MEK1/ERK/ELK1 signaling in hepatocellular carcinoma.
Academic Article miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling.
Academic Article Porphyria.
Academic Article Peripheral Neuropathy and the Ceruloplasmin Gene.
Academic Article Correction: Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group.
Academic Article Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury.
Academic Article Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group.
Academic Article Pathogenesis and clinical features of the acute hepatic porphyrias (AHPs).
Academic Article International Porphyria Molecular Diagnostic Collaborative: an evidence-based database of verified pathogenic and benign variants for the porphyrias.
Academic Article Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No Influence on Drug-Induced Liver Injury.
Academic Article Severe and protracted cholestasis in 44 young men taking bodybuilding supplements: assessment of genetic, clinical and chemical risk factors.
Academic Article Pilot study of mitochondrial bioenergetics in subjects with acute porphyrias.
Academic Article Herbal and dietary supplement hepatotoxicity.
Academic Article Sex differences in vascular reactivity in mesenteric arteries from a mouse model of acute intermittent porphyria.
Academic Article Acute Hepatic Porphyrias: Review and Recent Progress.
Academic Article Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria.
Academic Article Baseline Hepatic Levels of miR-29b and Claudin are Respectively Associated with the Stage of Fibrosis and HCV RNA in Hepatitis C.
Academic Article Benefits of prophylactic heme therapy in severe acute intermittent porphyria.
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